Beta-Tubulin (1B6) Antibody
Tubulin is a small family of globular proteins in nearly all eukaryotic cells. The most common members of this family are α-tubulin and β-tubulin, the proteins that make up microtubules. To form microtubules, the dimers of α- and β-tubulin bind to GTP and assemble onto the (+) ends of microtubules while in the GTP-bound state. After a dimer is incorporated into microtubule, the molecule of GTP bound to the β-tubulin subunit eventually hydrolyzes into GDP through inter-dimer contacts along the microtubule filament. Thus, the binding of β-tubulin to GTP or GDP influences the formation of microtubules, and GTP cycle is essential for the dynamic instability of microtubule in cells.
Our product is a mouse monoclonal antibody, which was raised against the full-length β-tubulin of human origin. It is prepared as cell culture supernatant (~ 40 μg/ml) with 0.01% sodium azide. The β-tubulin (1B6) antibody detects β-tubulin of human and mouse origins. It can be used for immunologic applications such as Western blotting (WB, dilution range: 1:50 - 500).
Gene Symbol (ID): TUBB (Human)
Isotype: IgG2b
Molecular Weight: 50 kDa
Storage: Keep at 2 - 8°C upon arrival (stable for six months from the date of shipment). For long-term storage, make aliquots and keep them at -20°C or below. Avoid repeated freeze-and-thaw cycles.
Jiagen Biotechnologies supplies quality Beta-Tubulin (1B6) antibody and customs antibody development services. To place an order or for more information, please contact us at sales@jiagen.com.